Dennis Simon, MD

  • Assistant Professor of Critical Care Medicine
  • Director, Pediatric Neurocritical Care
  • Site Director, Pediatric Neurocritical Care Fellowship

    Education & Training

  • BS, Biology and Biochemistry, Duke University, 2002
  • MD, SUNY Stony Brook, 2006
  • Residency, Pediatrics, Boston Combined Program, 2009
  • Residency, Chief Resident, Pediatrics, Boston Combined Program, 2010
  • Fellowship, Pediatrics Critical Care Medicine, UPMC Children’s Hospital of Pittsburgh, 2014
Harvard Medical Students Faculty Teaching Award, 2011
In-training Award, Society of Critical Care Medicine, 2013
Nancy Caroline Fellowship Award, Safar Center for Resuscitation Research, 2013
Pediatric Critical Care Faculty Teacher of the Year, UPMC Children’s Hospital Pittsburgh, 2016
Representative Publications

Simon DW, McGeachy MJ, Bayır H, Clark RS, Loane DJ, Kochanek PM. The far-reaching scope of neuroinflammation after traumatic brain injury. Nature Reviews Neurology. 2017 Mar;13(3):171.

Simon DW, Aneja RK, Alexander H, Bell MJ, Bayır H, Kochanek PM, Clark RS. Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Post-Natal Day 17 Rats. Journal of neurotrauma. 2018 Jan 1;35(1):130-8.

Wallisch JS, Simon DW, Bayır H, Bell MJ, Kochanek PM, Clark RS. Cerebrospinal fluid NLRP3 is increased after severe traumatic brain injury in infants and children. Neurocritical care. 2017 Aug 1;27(1):44-50.

Carcillo JA, Halstead ES, Hall MW, Nguyen TC, Reeder R, Aneja R, Shakoory B, Simon DW. Three hypothetical inflammation pathobiology phenotypes and pediatric sepsis-induced multiple organ failure outcome. Pediatr Crit Care Med. 2017 June; 18(6): 513-523.


► Full listing on Pub Med

Research Interests
  • Neurocritical care
  • Neuroinflammation
  • Microbiome in critical illness
  • Pediatric neurocritical care training