May 18, 2023: 20th Annual Safar Symposium: Paradigm Shifts in Brain Injury Research

The Safar Symposium is an annual, two-day multi-departmental event at the University of Pittsburgh School of Medicine that honors the late resuscitation pioneer Dr. Peter Safar. It includes scientific sessions with renowned speakers in both resuscitation science and simulation crafted by the faculty of the Safar Center for Resuscitation Research and the Winter Institute for Simulation, Education, and Research, respectively. The annual Peter and Eva Safar Lecture for the Sciences and Humanities is also part of the program. The Symposium also includes a multi-departmental Trainees' Research Day session with poster and platform presentations by trainees from five departments, namely Anesthesiology and Perioperative Medicine, Critical Care Medicine, Emergency Medicine, Neurological Surgery, and Physical Medicine & Rehabilitation.

42nd Peter and Eva Safar Lecture for the Sciences and Humanities

Guest Speaker: Geoffrey T. Manley, MD, PhD

Professor and Vice Chairman, Neurological Surgery, University of California San Francisco
Chief of Neurosurgery, Zuckerberg San Francisco General Hospital
Co-Director, Brain and Spinal Injury Center, San Francisco, CA

Dr. Geoffrey T. Manley is the Chief of Neurosurgery at Zuckerberg San Francisco General Hospital (ZSFG) and is Professor and Vice Chairman of Neurosurgery at the University of California, San Francisco. Dr. Manley is an internationally recognized expert in neurotrauma. In addition to a robust clinical practice at ZSFG, San Francisco, and the Greater Bay Area’s level 1 trauma center, he coordinates and leads national and international clinical research efforts in the study of the short- and long-term effects of TBI. With a nationwide team of TBI experts, has recently launched the TRACK-TBI NETWORK, an innovative, precision-medicine-driven consortium that will test Phase 2 drugs for TBI.

The TRACK-TBI studies have created a modern precision medicine information commons for TBI that integrates clinical, imaging, proteomic, genomic, and outcome biomarkers to drive the development of a new TBI disease classification system, which could revolutionize diagnosis, direct patient-specific treatment, and improve outcomes. His over 300 published manuscripts reflect a wide range of research interests from molecular aspects of brain injury to the clinical care of TBI.

He sits on the National Academies of Science, Engineering and Medicine’s Committee on VA Examinations for Traumatic Brain Injury and has served as a consultant for the Prehospital Guidelines Committee for the World Health Organization and on numerous clinical research committees for the National Institutes of Health, Centers for Disease Control, and Department of Defense.