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Actively Recruiting Studies

As of May 24, 2017

 

Industry-Sponsored Current Studies

PUH /
MUH
ICUs

PUH /
MUH
Floors

PUH
ED

Mercy
ED

Mercy ICU Shadyside Shadyside ICU

Out-
Patient
Clinic

UPMC Altoona

ATB-202

PI - Jason Sperry

A study to demonstrate the efficacy of AB103 as compared to placebo, in patients diagnosed with NSTI.

X   X            

BioMS Center

PI - Nathan Yates / Stacy Wendell


Biomedical Mass Spectrometry Center

                 

BMS Site (A14710491)

PI - Florian Mayr


A Phase 1b/2a, Randomized, Double-Blinded, Placebo-Controlled, Multi-center Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Subjects with Severe Sepsis

X                

CAPNIA

PI - Raymond Sekula


A Placebo-Controlled, Single-Blind Study Evaluating the Safety and Efficacy of Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia

              X  

MAPLE

PI - David Huang


The purpose of this ancillary study is to measure the human microbiome as a third readout for the impact of implementation of a procalcitonin-guided strategy.

    X X          

Octaplex

PI - Louis Alarcon


A Phase III, randomized, double-blind, multicenter study to assess the efficacy and safety of OCTAPLEX, a four-factor prothrombin complex concentrate (4F-PCC), compared to the 4F- PCC Beriplex® P/N (Kcentra), for the reversal of vitamin K antagonist induced anticoagula- tion in patients needing urgent surgery with significant bleeding risk.

X   X            

Opportunistic Viremia

PI - Ali Al-Khafaji / John Kellum


An Ex-vivo study of the effectiveness of the Aethlon Hemopurifier to extract viruses from the plasma of patients with suspected viremia in an ICU.

X                

Reset

PI - Laura DeCastro


Demonstrate efficacy of rivipansel in treating subjects with SCD who are older than 6 years of age experiencing an acute VOC event necessitating hospitalization.

  X              
Industry-Sponsored Current Studies Presby / Montefiore ICUs Presby / Montefiore Floors Presby Emergency Dept. Mercy Emergency Dept. Mercy ICU Shadyside Shadyside ICU Out-Patient Clinic Visits UPMC Altoona

Reset Extension

PI - Laura DeCastro


Open label extension study to evaluate the safety of Rivipansel (GMI-1070) in the treatment of one or more vasoocclusive crises in hospitalized subjects with sickle cell disease.

  X              

Sepsis ACT

PI - Hyung Kim


Selepressin Evaluation Programme for Sepsis-Induced Shock - Adaptive Clinical Trial. A  Double-blind, Randomised, Placebo-controlled, Phase 2b/3 Adaptive   Clinical Trial  Investigating the Efficacy and Safety of  Selepressin as  Treatment for Patients with Vasopressor-dependent Septic Shock

X                

STOP-AKI/AM Pharma

PI - Ragi Murugan


Evaluation of an extended release formulation of ondansetron for gastroenteritis/gastritis. RHB-102 (Bimodal Release Ondansetron) for Acute Gastroenteritis or Gastritis

X                

TTMR (TEG to Monitor RivaroXaban)

PI - Matthew Neal


Unitization of thromoelastography to monitor Rivaroxaban Activity in trauma and emergency surgery patients

      X          

VTL-208/208 Extension

PI - Ali Al-Khafaji


A randomized, open-label, multi-center, controlled study to assess safety and efficacy of  ELAD® in subjects with acute Alcoholic hepatitis (AAH).

X X              

VTI-209 Pharmoeconomics

PI - Ali Al-Khafaji


Tracking of economic data of subjects participating in all Vital Therapies Inc. sponsored ELAD®  studies in the United States.

X X              

VTI-308/308 Extension

PI - Ali Al-Khafaji


A Randomized, Open-label, Multicenter, Controlled, Pivotal Study to Assess  Safety and Efficacy of ELAD® in Subjects with Alcohol-Induced Liver  Decompensation (AILD)

X X              
Federally-Funded Current Studies Presby / Montefiore ICUs Presby / Montefiore Floors Presby Emergency Dept. Mercy Emergency Dept. Mercy ICU Shadyside Shadyside ICU Out-Patient Clinic Visits UPMC Altoona

Abdominal Sepsis/BVSRT

PI - Brian Zuckerbraun


A study to determine the role and mechanisms of erythroid DAMPs to potentiate vascular and acute lung injury in sepsis

X   X            

CAPSIL (Coordinating Center)

PI - Nina Singh


Prophylaxis versus Preemptive Therapy for the Prevention of CMV in High-Risk R-D+ Liver Transplant Recipients

                 

Comex

PI - Minisha Jhamb


Comprehensive Exercise (COMEX) program for dialysis patients pilot study

              X  

CureGN

PI - Herbert Rondon / Agnieszka Swiatecka-Urban


The collection of blood and urine samples to study glomerular disease

              X  

EPR-CAT

PI - Forsythe


Feasibility of Emergency Preservation and Resuscitation for Cardiac Arrest from Trauma

    X            

Endothelial Function & Systemic Inflammation

PI - Gregory Kato


Collection of blood from volunteers and patients for studies of endothelial function and systemic inflammation

                 

ESETT

PI - Alexandra Popescu


Randomized trial of valproic acid, fosphenytoin or dilantin for benzodiazepine refractory seizures.

    X X          

LITES (Coordinating Center)

PI - Jason Sperry


Linking Investigations in Trauma and Emergency Services (LITES) Network

                 

MATH Modeling

PI - Jason Sperry


Mathematical modeling of the acute inflammatory response following injury

X   X            
Federally-Funded Current Studies Presby / Montefiore ICUs Presby / Montefiore Floors Presby Emergency Dept. Mercy Emergency Dept. Mercy ICU Shadyside Shadyside ICU Out-Patient Clinic Visits UPMC Altoona

Neuromuscular Blockade (NMB) Blood Draw Study for Post-Cardiac Arrest Care *

PI - Jon Rittenberger


Comparing E-G-1962 to Standard of Care Oral Nimodipine in Adults with Aneurysmal Subarachnoid Hemorrhage.

X                

PAMper (Coordinating Center & Participating Site)

PI - Jason Sperry


A study to see if giving a plasma transfusion early in the course of treatment would help lower mortality of severely injured patients that lose a lot of blood (hypovolemic shock)

    X           X

POINT

PI - Matthew Starr


Platelet-Oriented Inhibition in New TIA and Minor Ischemic stroke

X X X     X      

ProACT (Coordinating Center & Participating Site)

PI - David Huang / Aaron Brown


Study goal is to determine if implementation of a procalcitonin antibiotic algorithm can help clinician safely decrease antibiotic use in ED lower respiratory tract infection.

    X X          

ProGReSS AKI ConsequenceS

PI - Sachin Yende


Long term outcomes of sepsis

X                

Rose

PI - David Huang


Reevaluation of systemic early neuromuscular blockade

X       X   X    

SHINE

PI - Lori Shutter


Management of glucose after stroke

X   X X X        

STAAMP (Coordinating Center & Participating Site)

PI - Jason Sperry


Study of tranexamic acid during air medical prehospital transport.

    X            

Vascular Access Questionnaire

PI - Natalie Domenick-Sirdhan


Extracorporeal liver assist device for alcohol induced liver decompensation

              X  
Foundation-Funded Current Studies Presby / Montefiore ICUs Presby / Montefiore Floors Presby Emergency Dept. Mercy Emergency Dept. Mercy ICU Shadyside Shadyside ICU Out-Patient Clinic Visits UPMC Altoona

AWAKE*

PI - Jon Rittenberger


A study to evaluate the effect of amantadine on speeding awakening after resuscitation from cardiac arrest.

X                

Surprise Question

PI - Manisha Jhamb


Predicative modeling in older non-dialysis dependent CKD

              X  
Department-Funded Current Studies Presby / Montefiore ICUs Presby / Montefiore Floors Presby Emergency Dept. Mercy Emergency Dept. Mercy ICU Shadyside Shadyside ICU Out-Patient Clinic Visits UPMC Altoona

Baxter

PI - Raymond Sekula


A Randomised Controlled Study to Evaluate the Effectiveness and Safety of Fibrin Sealant, Vapour Heated, Solvent/Detergent Treated (FS VH S/D 500 s apr) Compared to DuraSeal Dural Sealant as an Adjunct to Sutured Dural Repair in Cranial Surgery.

X         X      

GENE-EKG/Angiography CRDF

PI - Salah Al-Zaiti


Non St elevation myocardial ischemia: The Role of Cell Survival Genes

X                

Sprint-Sari

PI - David Wallace


The primacy aim of this study is to establish a research response capability for a future epidemic and pandemic through a global SARI observational study.

                 

 

 

*Sample Processing Only