Left to right: Mary Kruth, Denise Scholl, Ashley Ryman, Dan Unikel, Barbara Early, Andrew Jockers, Pam Fazio, Pete Adams, Stacy Stull, Meghan Buck, Mary Stefanick
On June 8, 2015 MACRO began screening for STOP-AKI and enrolled the first subject in August.
This is a randomized, double-blind, placebo-controlled, four-arm, parallel-group, proof of concept, dose-finding, adaptive, phase 2a/2b study to investigate the safety, tolerability and efficacy and effect on quality of life of human recombinant alkaline phosphatase (recAP) in the treatment of patients with sepsis-associated acute kidney injury (SA-AKI).
The primary objectives are:
Dr. Raghavan Murugan is the Principal Investigator and MACRO’s lead coordinator is Pam Fazio.
On October 1, 2015, MACRO began screening and enrolling for ATHOS3(Angiotensin II for the Treatment of High-Output Shock). Since opening, there have been four enrollments. Dr. Raghavan Murugan is the Principal Investigator and MACRO’s lead coordinator is Andrew Jockers.
ATHOS3 is a phase 3, placebo-controlled, randomized, double-blind, multicenter study sponsored by La Jolla Pharmaceutical Company, Inc. The purpose of this study is to test a new drug called LJPC-501 (also known as angiotensin II) in patients with Catecholamine-Resistant Hypotension (CRH).
Erin graduated from the University of Pittsburgh in April 2015, where she majored in Psychology and Sociology. While studying at Pitt, Erin worked as a MACRO Research Associate (RA) for 4 years. In August 2015, she began working full time with MACRO. Currently, she assists with undergraduate RA intern administration and training as well as trauma study administrative tasks. To date, her greatest accomplishment was being voted best Penguins fan by her colleagues!
On August 13th, MACRO Research Associate (RA) alum (2012), Patrick Coppler, first authored a publication in Prehospital Emergency Care on Accuracy of Prehospital Intravenous Fluid Volume Measurement by Emergency Medical Services. Click here to read the full article.
Patrick Coppler began working for MACRO as a RA in August 2012. After graduating from the University of Pittsburgh in December 2012, where he majored in Music and minored in Neuroscience; Patrick continued working with MACRO as a Graduate Student Researcher on multiple trials at Mercy and Presbyterian.
In September 2014, Patrick began at the University of the Sciences in Philadelphia, PA to obtain his Physician’s Assistant degree.
We hope to collaborate with Patrick as one of our PIs in the near future!
On October 14th, MACRO Clinical Coordinator Director Barbara Early served on a panel discussion at the Model Agreements & Guidelines International (MAGI) Clinical Research Conference in San Diego. The discussion was entitled “Site Operations Challenges: Do You Really Expect Us to Do This? - What happens when a sponsor or CRO makes ‘unreasonable’ demands on a site?”
MACRO Financial Manager Dan Unikel was the keynote speaker for the Greater Pittsburgh Chapter of the Association of Clinical Research Professionals (ACRP) Educational Dinner on November 4th. During the dinner, Dan presented his take on financial management with his presentation entitled “Healthy Habits to Keep Clinical Research out of the Financial Emergency Room.”