Posted by on Tue, 09/09/2014 - 11:12am
JAMA Intern Med. Published online September 08, 2014. doi:10.1001/jamainternmed.2014.4056
Meta-analysis of RCTs comparing intermitent vs. continuous in patients with GI bleeding and high rebleed risk found no difference (actually a trend to intermittent dosing being better). So why do we use continuous PPI and tie up an extra IV and waste healthcare dollars?
Posted by on Thu, 07/10/2014 - 8:26am
Reference courtesy of Dr. Shutter, these authors evaled whether family presence during brain death examination improved understanding of brain death. In short it seemed to work, as families at all levels of education demonstrated improved understanding, based on answers to questions such as "Can someone who is brain dead ever wake up/recover?". Concordant with a larger body of literature supporting family presence during invasive procedures, resuscitation etc. so likely a worthwhile discussion.
Posted by on Wed, 07/02/2014 - 8:42am
Though results of this study are difficult to generalize to all neurosurgical patients, nice paper about optimal transfusion threshold for these patients.
Posted by on Tue, 04/29/2014 - 12:45pm
Eric Juttler et al. Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke
Roper A. Hemicraniectomy — To Halve or Halve Not (editorial) NEJM March 20, 2014
Good study on outcomes of hemicraniectomy, and raises important issues on quality of life, appropriate outcomes for evaluation and value of new procedures.
Posted by on Sun, 03/23/2014 - 10:32pm
Nice observational study in JAMA examining epidemiologic of sepsis in Australia over several years.
Posted by on Tue, 02/25/2014 - 12:49pm
This topic has been visited several times, but maybe this will be the last?
Posted by on Sun, 11/17/2013 - 8:27pm
This topic has been beaten to death but this is an interesting trial because it looks at early fluid resuscitation unlike the previous trials.
Posted by on Sun, 11/17/2013 - 8:25pm
I think there has been some discussion about using this system here. The trial looks at the LUCAS chest compression system for cardiac arrest.
Posted by on Sun, 11/17/2013 - 8:22pm
RCT looking at pre-hospital hypothermia.
Posted by on Wed, 08/14/2013 - 11:27am
I thought this would be a paper worth circulating, and despite it is a systematic review, maybe would lend ground to discuss what our position as a department would be to use this tool. Would be great to have our neurointensivists for example weight into the discussion, and finish up with a draft consensus of how the "EEG pitt way" should look like.
Here it is: http://icmjournal.esicm.org/journals/abstract.html?v=39&j=134&i=8&a=2938...
Posted by on Mon, 08/05/2013 - 12:30pm
This August 2013 NEJM randomizd trial of intraoperative, prophylactic low tidal volume ventilation dovetails nicely with the October 2012 JAMA meta-analysis presented at our March 2013 Journal Club (below).
Posted by on Tue, 07/30/2013 - 10:27am
Findings are in contrast to previous studies and may be worth discussing why.
Posted by on Tue, 07/30/2013 - 10:19am
Interesting paper and would be good to work with Doug.
Posted by on Tue, 07/30/2013 - 10:12am
We did a similar paper a year ago but these findings are different. It is a good opportunity to discuss a meta-analysis.
Posted by on Tue, 07/30/2013 - 10:02am