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Which central line site should I choose? N Engl J Med 2015;373:1220-9.

Required reading for all intensivists! This is a well done RCT where EXPERIENCED personnel placed central lines in each of the 3 major positions. Limitation: limited US use especially at the femoral site but little difference in insertion times or arterial injury. The results confirm what's long been suspected- subclavians have the least infections/clots but more pneumos.

Link: http://www.nejm.org/doi/full/10.1056/NEJMoa1500964?query=TOC

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