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Journal Club Blog

Hi folks,

Welcome to the Journal Club Blog for our department. The goal of this blog is to briefly discuss important papers and serve as a resource for fellows to choose papers for journal club.

Ground rules: Keep discussion brief (500 words) and courteous. Provide links to articles for others to retrieve and avoid posting sensitive info (site isn't password protected).

Happy blogging!!

Let Christy and me know about any problems/suggestions.

Sachin

Comments

The optimal target for mean arterial pressure in severe sepsis in unknown. Nice paper examining higher MAP targets aren't helpful. Consider discussing this paper in the context of pathophysiology of sepsis and sepsis induced AKI.

http://www.nejm.org/doi/full/10.1056/NEJMoa1312173#t=articleBackground

 

Albumin replacement in severe sepsis wasn't helpful. 

http://www.nejm.org/doi/full/10.1056/NEJMoa1305727

 

http://www.nejm.org/doi/full/10.1056/NEJMoa1401520

Lots of interest about role of statins for ARDS and severe sepsis. This study is one of the largest RCT and showed no benefit.

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