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Penny Lynn Sappington, MD

Assistant Professor, CCM, University of Pittsburgh School of Medicine

Medical Director, Cardiothoracic/Surgical Intensive Care Unit, UPMC Presbyterian

Admin Assistant: Joanne Woodson

Penny Lynn Sappington graduated with a Bachelor of Arts Degree in Biological Sciences from the North Carolina Agricultural and Technical State University in Greensboro, North Carolina in 1989.  She received her Medical Degree from the Pennsylvania State University College of Medicine in 1994.  From 1994 through 1997 she completed a three-year residency in Internal Medicine at Howard University in Washington, DC.  Subsequently, she completed a two-year fellowship in Infectious Diseases at Howard University Hospital in Washington, DC (1997-1999), and this was followed by a fellowship in Critical Care Medicine at the University of Pittsburgh Medial Center (1999-2000).  Dr. Sappington joined the Critical Care Medicine faculty in July 2000 as an Assistant Professor with appointment in Critical Care Medicine. 

She is currently an Assistant Professor of Critical Care Medicine in the recently created Department of Critical Care Medicine.  Dr. Sappington has been certified by the American Board of Internal Medicine (1997), and has received certificates of added qualifications in Infectious Diseases (1999) and Critical Care Medicine (2000).  Dr. Sappington received a patent in 2002 for Ethyl Pyruvate is an anti-inflammatory agent.



Education & Training




Pennsylvania State University MD 1994 Medicine
Howard University Hospital Resident 1997 Internal Medicine
Howard University Hospital Fellow 1999 Infectious Disease
University of Pittsburgh Fellow 2000 Critical Care Medicine


Administrative Titles 

Medical Director, CTICU, University of Pittsburgh Medical Center


Completed Research

National Institutes of Heath - “Ethyl Pyruvate: A Novel Treatment for Sepsis”

National Institutes of Health / National Institute of General Medical Sciences - “HMGB1 Alteration Tight Junction Structure and Function”



Bermudez CA, Rocha RV, Sappington PL, Toyoda Y, Murray HN, Boujoukos AJ. Initial experience with single cannulation for venovenous extracorporeal oxygenation in adults. Ann Thorac Surg. Sept 2010; 90(3): 991-995

Adalja A, Sappington PL, Harris, SP, Rimmele T, Kreit JW, Kellum JA, Boujoukos AJ.  (2011) Isolation of Aspergillus in three 2009 H1N1 influenza patients. Influenza and Other Respiratory Viruses DOI: 10.1111/j.1750-2659.2011.00202.x.