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Kate Kernan, MD, MFA

Fellow, Pediatric Critical Care


Education & Training




College of the Holy Cross




 University of Pennsylvania




New England College MFA 2012 Poetry

 St. Louis Children’s Hospital, University of Washington




 Children’s Hospital of Pittsburgh of UPMC



Pediatric Critical Care Medicine

Ongoing Research

Sepsis Phenomes

Completed Research

Quantitative genomic study of the inflammatory affects of alcohol dependence and withdrawal in rats on the nucleus tractus solitarius and amygdala

Presentations at Meetings

"Systems biology in alcohol addiction and withdrawal: This is your brain on drugs.”Japan-United States Cooperative Brain Research Workshop. 2010.

"Genetic variants associated with hyperinflammation in septic shock". Kate Kernan, MD; Lina Gonzalez, MD; Rahil Sethi, BS; Uma Chandran, PhD, MSIS; Janette Lamb, PhD; John A. Kellum, MD, MCCM; Derek Angus, MD, MPH, MCCM and Mentor: Joseph Carcillo, MD. Poster Presentation. 46th SCCM Critical Care Congress, 2017


Kate Kernan and Robert Kennedy. “Emergencies”. The Washington Manual of Pediatrics. 2nd Edition. Ed. Andrew White. Philadelphia: Wolters Kluwer, 2016. 33-49. Print.

James Park, Anthony Brureau, Kate Kernan, Alexandria Starks, Sonali Gulati, Babatunde A. Ogunnaike, James S. Schwaber, Rajanikanth Vadigepalli. Inputs Drive Cell Phenotype Variability. Genome Res. 2014 Jun;24(6):930-41. PMID:24671852

Kate Freeman, Mary M. Staehle, Rajanikanth Vadigepalli, Gregory E. Gonye, Babatunde A. Ogunnaike, Jan B. Hoek, James S. Schwaber. Coordinated dynamic gene expression changes in the Central Nucleus of the Amygdala during alcohol withdrawal. Alcoholism: Clinical and Experimental Research. 2013 Jan;37 Suppl 1:E88-100. PMID: 22827539

Rachel L. Yang, Kate Freeman, Caroline E. Reinke, Douglas L. Fraker, Giorgos Karakousis, Rachel R Kelz, Alden Doyle. Tertiary Hyperparathyroidism In Kidney Transplant Recipients: Characteristics of Patients Selected for Different Treatment Strategies. Transplantation. 2012 Jul 15;94(1):70-6. PMID:22706321

Kate Freeman, Anthony Brureau, Rajanikanth Vadigepalli, Mary M Staehle, Melanie M Brureau, Gregory E Gonye, Jan B Hoek, D Craig Hooper and James S Schwaber. Temporal changes in innate immune signals in a rat model of alcohol withdrawal in emotional and cardiorespiratory nuclei. Journal of Neuroinflammation 2012 May 24, 9:97. PMID: 22626265

Kate Freeman, Mary M. Staehle, Zeynep H. Gümüş, Rajanikanth Vadigepalli, Gregory E. Gonye, Carmen N. Nichols, Babatunde A. Ogunnaike, Jan B. Hoek, James S. Schwaber. Rapid temporal changes in the expression of a set of neuromodulatory genes during alcohol withdrawal in the dorsal vagal complex: molecular evidence of homeostatic disturbance. Alcoholism: Clinical and Experimental Research 2012 Oct;36(10):1688-700. PMID: 22486438

Rachel R. Kelz, Kathryn M. Freeman, Patrick W. Hosokawa, David Asch, Francis R Spitz, Miriam Moskowitz, and William G. Henderson. Time of day affects post-operative morbidity:  an analysis of the national surgical quality improvement program data. Annals of Surgery. Mar 247(3):544-52, 2008. PMID:18376202

Freeman, K, Hoffmann, GR. Frequencies of mutagen-induced coincident mitotic recombination at unlinked loci in Saccharomyces cerevisiae. Mutation Research, Mar 1;616(1-2):119-32, 2007 . PMID:17156798