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Christopher W. Seymour, MD, MSc

Assistant Professor, Departments of Critical Care and Emergency Medicine

Admin Assistant: Jackie Toboz

Dr. Seymour is Assistant Professor of Critical Care and Emergency Medicine at the University of Pittsburgh School of Medicine. He is core faculty member in the Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Center in the Department of Critical Care, where he contributes to the Program on Critical Care Health Policy. He is affiliated faculty in the Center for Research on Emergency Medical Services (CREMS) in the Center for Emergency Medical Services of Western Pennsylvania. Dr. Seymour received his medical degree from the University of Pennsylvania before completing his internship and residency in Internal Medicine at the Hospital of the University of Pennsylvania. He then completed a fellowship in Pulmonary and Critical Care Medicine at the University of Washington, where he obtained masters degree in clinical epidemiology at the University of Washington, School of Public Health. Prior to joining the faculty at the University of Pittsburgh, he was instructor at the University of Washington.

Dr. Seymour’s research program focuses on the organization of critical care during pre-hospital care – particularly the development of early diagnostic and prognostic models to facilitate allocation of patients and early treatments for those with acute illness. Specifically, he seeks to develop a research and acute care paradigm for pre-hospital sepsis similar that for acute cardiovascular disease. He has been awarded grants from the National Institutes of Health, Society of Critical Care Medicine, American Heart Association, and MedicOne Foundation. He spends his clinical time attending the Medical Intensive Care Unit at UPMC-Mercy Hospital.

Dr. Seymour lives in Pittsburgh with his family and two dogs. In his spare time, he enjoys amateur photography, cycling, and multiple agricultural hobbies.


Education & Training




Duke University, Durham, NC



Biology, Mathematics

University of Pennsylvania School of Medicine, Philadelphia, PA




University of Washington School of Public Health, Seattle, WA





Administrative Titles


 2011 – Present

 Critical Care Medicine

Core Faculty, Clinical Research, Investigation and Systems Modeling of Acute Illness (CRISMA) Center

 2011 - Present

 Emergency Medicine

Affliated Faculty, Center for Research on Emergency Medical Services





Global Rising Star in Intensive Care - Australia New Zealand Intensive Care Society


NIH Loan Repayment Award


Society of Critical Care Medicine Vision Grant 


American Thoracic Society, Critical Care Travel Award


Maurice Attie Senior Resident Teaching Award, Hospital of the University of Pennsylvania Internal Medicine Residency


 Konovsky Prize in Internal Medicine, University of Pennsylvania School of Medicine


 David Goodman Award in Clinical Research, University of Pennsylvania School of Medicine


Pinckus Prize for Achievement, University of Pennsylvania School of Medicine


Alpha Omega Alpha, Junior Inductee, University of Pennsylvania School of Medicine


Graduate, Magna Cum Laude, Duke University


Phi Beta Kappa, Duke University


Ongoing Research Projects:

PIttsburgh Prehospital LINking Evaluation (PIPeLINE) study

Think Sepsis App for EMS

Immune Regulation of RNA metabolites in sepsis

Murine models of prehospital care


Completed Research Projects:

Tiered regionalization of critically ill patients during out-of-hospital care: an impact analysis

Out-of-hospital shock in non-injured patients: risk stratification and early resuscitation


See Dr. Seymour's Research Investigator Page



Recent publications:

Severe Sepsis in Prehospital Emergency Care: Analysis of Incidence, Care, and Outcome
Christopher W Seymour, Thomas D Rea, Jeremy M Kahn, Allan Walkey, Donald M Yealy, and Derek C Angus, published 18 October 2012, 10.1164/rccm.201204-0713OC

Seymour CW, Kahn JM, Cooke CR, Watkins TR, Heckbert SR, Rea TD. Prediction of critical illness during out-of-hospital emergency care. JAMA. 2010;304(7):747-754.

Seymour CW, Cooke CR, Hebert PM, Rea TD. Pre-hospital intravenous access among non-injured patients: a population-based outcomes study. Ann Emerg Med 2011 (in press)

Seymour CW, Iwashyna TI, Ehlenbach, WJ, Wunsch H, Cooke CR. Hospital level variation in the use of intensive care. Health Serv Res (in press)

See more of Christopher Seymour's Publications