About the PANGEA study

Acute critical neurologic injury in children due to traumatic brain injury, cardiac arrest, stroke, seizures, central nervous system infection, and spinal cord injury is associated with significant morbidity and mortality and enormous economic burden worldwide.

Treatment for acute brain injury in children is largely supportive and new therapies are critically needed.

PANGEA is a point prevalence study will acquire data on children with acute brain injury over 4 study dates in over 70 sites around the world.

The short term objective of this international multi-center point prevalence study is to describe the epidemiology and gross outcomes of acute critical neurologic disease in children.

The long term objectives of this study are four-fold:
1) To improve outcomes in children with acute critical neurologic disease,
2) To assist in the design of prospective clinical research,
3) To address the allocation of healthcare resources for treatment and rehabilitation, and
4) To develop a network for communication and collaborations across the globe.

Study dates: Complete

Principal Investigator: Ericka L. Fink, MD
Assistant Professor
Dept. Critical Care Medicine
Children's Hospital of Pittsburgh, PA USA